GBI Research, a leading business
intelligence provider, has released its latest research report, "Non-Small
Cell Lung Cancer Market to 2020 - New Therapies to Enhance Treatment
Segmentation and Drive Growth in an Increasingly Competitive Market". The
value of the Non-Small Cell Lung Cancer (NSCLC) market is expected to increase
significantly over the forecast period across the leading eight developed
nations, from $5.1 billion in 2013 to $7.9 billion in 2020. This equates to a
Compound Annual Growth Rate (CAGR) of 6.6%. Growth will be driven by novel
therapies entering the squamous cell carcinoma market segment, which is
currently lacking effective treatment, unlike the non-squamous market segment.
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The
report focuses on the increasing differentiation between the three main NSCLC
subtypes: squamous cell, adenocarcinoma, and large cell carcinoma. Common
genetic and molecular aberrations within these histologies are being
extensively researched and targeted by novel therapeutics and so the treatment
algorithm between histological subtypes is forecast to become more
differentiated over the forecast period. Most notably, patients with squamous
cell carcinoma are set to benefit from crucial first- and second-line therapies
in the form of Yervoy (ipilimumab) and nivolumab, having relied on generic
chemotherapy for the past decade. Non-squamous patients, on the other hand,
have several successful histology-specific therapies, such as Alimta
(pemetrexed), and mutation-specific therapies, such as Tarceva (erlotinib),
that are already marketed. New second-line entrants will create a crowded and
competitive environment. The generic erosion of market leaders Alimta and
Tarceva late in the forecast period will make this a tough environment for new
products that have shown only minor improvements in safety or efficacy.
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