GBI Research, a leading business
intelligence provider, has released its latest research report, "Melanoma
Therapeutics Market to 2020 - Rising Prevalence and Evolving Treatment
Algorithms to Drive Market Growth"
Melanoma is a highly
heterogeneous disease comprising Cutaneous Melanoma (CM), Ocular Melanoma (OM),
Mucosal Melanoma (MM), melanoma of the internal organs, and, according to some
classifications, melanoma of the soft parts (non-bony and non-cartilaginous
tissues) of the body. CM is by far the most common form of melanoma, accounting
for approximately 90-95% of all melanomas.
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Historically, melanoma has been
considered as a very challenging disease to treat with pharmacotherapy.
However, in recent years, understanding of the pathophysiology and
heterogeneity of melanoma, and particularly CM, has developed considerably.
This has led to the approval of several new drug agents indicated for CM since
2011, namely Sylatron (peginterferon alfa-2b), Yervoy (ipilimumab), Opdivo,
(nivolumab), Keytruda (pembrolizumab), Zelboraf (vemurafenib), Tafinlar (dabrafenib)
and Mekinist (trametinib). These drugs have dramatically improved the treatment
options for CM patients, leading to unprecedented market growth.
Rapid market growth is also
anticipated over the forecast period due to the expanding melanoma treatment population
and the continued uptake of recently approved drugs. The melanoma pipeline is
currently strong, with several promising molecules in development including,
Polynoma's seviprotimut-L, Amgen's talimogene laherparepvec (T-VEC) and Roche
and Genentech's cobimetinib in combination with Zelboraf, which are in
development for CM, as well as AstraZeneca's selumetinib which is in
development for OM. Consequently, the melanoma therapeutics market is projected
to grow from $1.3 billion in 2013 to $3.6 billion in 2020, at a CAGR of 15.4%.
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